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Merekar, A. N.
- Synthesis and Evaluation of Some New Substituted 1, 4-Dihydropyridine Derivatives and Their Anti-Inflammatory Activity
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Authors
S. R. Pattan
1,
N. S. Dighe
1,
S. V. Hiremath
2,
A. N. Merekar
3,
V. M. Gaware
1,
D. S. Musmade
1,
P. M. Gaikwad
4
Affiliations
1 Dept of Pharmaceutical Chemistry, Pravara Rural College of Pharmacy, Pravaranagar, Loni-413713, IN
2 Dept of Pharmacology, J.N Medical College, Belgaum, IN
3 Dept of Pharmaceutics, Pravara Rural College of Pharmacy, Pravaranagar, Loni-413713, IN
4 Dept of Pharmacology, Pd. Dr. Vitthalrao Vikhe Patil College of Pharmacy, Ahmednagar, IN
1 Dept of Pharmaceutical Chemistry, Pravara Rural College of Pharmacy, Pravaranagar, Loni-413713, IN
2 Dept of Pharmacology, J.N Medical College, Belgaum, IN
3 Dept of Pharmaceutics, Pravara Rural College of Pharmacy, Pravaranagar, Loni-413713, IN
4 Dept of Pharmacology, Pd. Dr. Vitthalrao Vikhe Patil College of Pharmacy, Ahmednagar, IN
Source
Asian Journal of Research in Chemistry, Vol 2, No 3 (2009), Pagination: 310-313Abstract
A new series if substituted 1, 4-Dihydropyridine derivatives were synthesized and the structures of these compounds were established on the basis of spectral and elemental analysis. All the compounds were evaluated for anti-inflammatory activity by paw edema, xylene induced ear edema and cotton wool granuloma methods. Compounds C4, C5, C6, C7 and C9 have been found to exhibit excellent anti-inflammatory activity.Keywords
1, 4-Dihydropyridine, Anti-Inflammatory, CHN Analysis.- Synthesis and Biological Evaluation of Some Substituted Amino Thiazole Derivatives
Abstract Views :150 |
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Authors
Affiliations
1 Department of Medicinal Chemistry, Pravara Rural College of Pharmacy, Pravaranagar, IN
2 Department of Pharmacognosy, Pravara Rural College of pharmacy, Pravaranagar, IN
3 Department of Pharmaceutics, Pravara Rural College of Pharmacy, Pravaranagar, IN
1 Department of Medicinal Chemistry, Pravara Rural College of Pharmacy, Pravaranagar, IN
2 Department of Pharmacognosy, Pravara Rural College of pharmacy, Pravaranagar, IN
3 Department of Pharmaceutics, Pravara Rural College of Pharmacy, Pravaranagar, IN
Source
Asian Journal of Research in Chemistry, Vol 2, No 2 (2009), Pagination: 196-201Abstract
Thiazoles and their derivatives exhibit a wide variety of biological activities like antidiabetic, anti inflammatory, anticonvulsants etc.
In the present study we have synthesized some substituted thiazoles. These compounds were evaluated for various biological activities like Anti-diabetic,anti-inflammatory,anti-fungal activity.